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The primitive streak in a bird is the functional equivalent of ________.


A) the lip of the blastopore in the frog
B) the archenteron in a frog
C) the notochord in a mammal
D) neural crest cells in a mammal

E) C) and D)
F) A) and B)

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The first cavity formed during frog development is the ________.


A) blastopore
B) mouth
C) blastocoel
D) anus

E) A) and D)
F) A) and B)

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The term applied to a morphogenetic process whereby cells extend themselves, making the mass of the cells narrower and wider, is ________.


A) convergent extension
B) induction
C) invagination
D) involution

E) None of the above
F) A) and C)

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Just prior to the onset of gastrulation in an embryo, the "organiser" cells are specified. If you were to experimentally block the specification of these cells, what would you expect the result to be in the developing embryo?


A) There would be no effect on development.
B) Gastrulation would not occur, and normal development would cease.
C) The body axes would develop normally, but the embryo would not grow appendages.
D) The embryo would not develop an intestine, but all other organs and tissues would develop normally.

E) All of the above
F) None of the above

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The developmental precursors to the gonadal tissues of Caenorhabditis elegans uniquely contain ________.


A) proteins of maternal origin
B) high concentrations of potassium ions
C) T tubules for the propagation of action potentials
D) P granules of mRNA and protein

E) None of the above
F) B) and C)

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The archenteron develops into


A) the mesoderm.
B) the endoderm.
C) the placenta.
D) the lumen of the digestive tract.

E) B) and D)
F) A) and B)

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Embryonic induction, the influence of one group of cells on another group of cells, plays a critical role in embryonic development. In 1924, Hans Spemann and Hilde Mangold transplanted a piece of tissue that influences the formation of the notochord and neural tube, from the dorsal lip of an amphibian embryo to the ventral side of another amphibian embryo. If embryonic induction occurred, which of the following observations justifies the claim of embryonic induction?


A) The transplanted tissue induced multiple limbs to develop on the ventral side of the recipient embryo.
B) The transplanted tissue inhibited normal cell division on the dorsal side of the recipient embryo that lead to its death.
C) The transplanted tissue had no effect on either the ventral or dorsal side of the recipient embryo so it continued to develop normally.
D) The transplanted tissue induced the formation of a second notochord and neural tube on the ventral side of the developing embryo.

E) None of the above
F) All of the above

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Which of the following is common to the development of birds and mammals?


A) the formation of an embryonic epiblast and hypoblast
B) the formation of an embryonic trophoblast
C) the formation of an embryonic yolk plug
D) the formation of an embryonic grey crescent

E) B) and C)
F) A) and D)

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If the apical ectodermal ridge is surgically removed from an embryo, it will lose ________.


A) positional information for limb-bud pattern formation
B) guidance signals needed for correct gastrulation
C) unequal cytokinesis of blastomeres
D) the developmental substrate for the kidneys

E) C) and D)
F) None of the above

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The nematode Caenorhabditis elegans ________.


A) is composed of about 1,000 cells, in which the developmental origin of each cell has been mapped
B) has only a single chromosome, which has been fully sequenced
C) has about 1,000 genes, each of which has been fully sequenced
D) uniquely, among animals, utilises programmed cell death during normal development

E) A) and D)
F) B) and D)

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