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Invagination of the sea urchin blastula


A) is preceded by changes in the shape of individual blastomeres.
B) involves the filopodia of secondary mesenchyme cells.
C) is due to the uneven distribution of various transcriptional regulatory proteins in the egg cytoplasm.
D) forms the archenteron.
E) All of the above

F) D) and E)
G) A) and B)

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How is the development of the extraembryonic mem­branes different in birds and placental mammals and how is it similar? What accounts for the difference?

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Both the birds and mammals develop extra...

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If cells from the presumptive neural ectoderm of a frog gastrula are transplanted onto the surface of a second gastrula where skin would normally develop, the transplanted cells will still develop into tissues of the nervous system. This experiment shows that the transplanted cells are


A) differentiated.
B) totipotent.
C) discontinuous.
D) determined.
E) endodermal.

F) A) and E)
G) B) and E)

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The embryos of complex multicellular animals must establish spatial coordinates if development is to proceed. An important reference coordinate for developing frogs is the


A) location of the vegetal pole.
B) location of the animal pole.
C) point of sperm penetration.
D) location where gastrulation begins.
E) direction of the sun.

F) B) and D)
G) A) and D)

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How does cleavage in mammals differ from cleavage in frogs?


A) Slower rate of cell division
B) Formation of tight junctions
C) Expression of the embryo's genome
D) Early separation of cells that will not contribute to the embryo
E) All of the above

F) C) and D)
G) A) and D)

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Which statement about trophoblast cells is true?


A) They are capable of producing monozygotic twins.
B) They are derived from the hypoblast of the blastocyst.
C) They are endodermal cells.
D) They secrete proteolytic enzymes.
E) They prevent the zona pellucida from attaching to the oviduct.

F) B) and C)
G) A) and E)

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Which of the following statements about neurulation is false?


A) Neural crest cells give rise to peripheral nerves.
B) Body segmentation develops during neurulation.
C) Hox genes control differentiation along the anterior-posterior body axis.
D) Neural crest cells are migratory.
E) Neural crest cells break loose from the neural tube adjacent to the line of closure and remain there to contribute to a number of structures.

F) D) and E)
G) A) and E)

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_______ is a birth defect caused by the failure of the closure of the posterior region of the neural tube.

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The _______ is an important structure for waste storage in birds and some mammals, but not in humans.


A) allantois
B) yolk sac
C) placenta
D) umbilical cord
E) amnion

F) A) and E)
G) D) and E)

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The segmented characteristic of human embryonic development is evident from the bricklike structures called _______ that form along the notochord.


A) neural tubes
B) mesoderm
C) ectoderm
D) somites
E) somatomeres

F) B) and D)
G) B) and C)

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If a cell is removed from an eight-cell embryo, and a particular portion of the organism fails to form, the development is termed


A) regulative.
B) controlled.
C) banished.
D) irreversible.
E) mosaic.

F) B) and C)
G) A) and B)

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Which of the following does not occur during cleavage?


A) Rapid DNA synthesis
B) Cell growth
C) Differential distribution of nutrients and information molecules
D) A rapid series of cell divisions
E) Formation of the blastula

F) B) and C)
G) C) and D)

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During its development, the human embryo is contained within a fluid-filled chamber enclosed by the extraembryonic membrane called the


A) yolk sac.
B) amnion.
C) chorion.
D) allantois.
E) trophoblast.

F) A) and C)
G) A) and E)

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The period of human gestation is also called _______.

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In mammals, the sac that secretes fluid to form the blastocoel is called the _______.

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The primitive groove of bird and mammalian embryos is analogous to the _______ of amphibians and sea urchins.

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The third trimester of human prenatal development is characterized by


A) extremely rapid growth.
B) the formation of major organs.
C) the greatest sensitivity to damage from drugs and radiation.
D) gastrulation.
E) the formation of the placenta.

F) A) and E)
G) D) and E)

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Once development has proceeded to the point that three germ layers are in place within the embryo, the next phase of development, called _______, can begin.


A) organogenesis
B) gastrulation
C) hypoblasty
D) epiblasty
E) transcription

F) B) and C)
G) A) and E)

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During cleavage, the cytoplasm of new cells in a developing frog embryo


A) comes from the egg cytoplasm.
B) is synthesized by the blastomeres.
C) does not contain any yolk.
D) is the vegetal pole.
E) undergoes mitosis.

F) A) and B)
G) A) and C)

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Roughly how many Hox genes are there in mammals?


A) 4
B) 10
C) 40
D) 3,100
E) An unknown number; they have been studied in amphibians only.

F) A) and B)
G) A) and C)

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