Question 1

When use of a drug interferes with normal behavior,experienced users may learn to compensate and show less impairment than new users.This is an example of

Accepted Answer

A)  drug disposition tolerance.
B)  behavioral tolerance.
C)  an active metabolite.
D)  a prodrug.E) A) and C)
F) A) and B)

Question 2

Caffeine and cocaine are both considered to be stimulant drugs.

Accepted Answer

A) True 
 B)False

Question 3

According to the text,inexperienced drug users should avoid taking a drug via a route that increases the drug's potency.

Accepted Answer

A) True 
 B)False

Question 4

With increasing doses of any useful drug,there is usually an increase in the number and severity of

Accepted Answer

A)  side effects.
B)  beneficial effects.
C)  placebo effects.
D)  effects on the stomach.E) All of the above
F) A) and C) A

Question 5

Nonspecific effects of taking a drug are those that do not depend on its chemical activity.They are sometimes referred to as

Accepted Answer

A)  placebo effects.
B)  ataxia.
C)  side effects.
D)  dose-response effects.E) B) and D)
F) A) and D)

Question 6

If repeated exposure to a drug increases the activity of the CYP450 enzyme that is responsible for metabolizing that drug,then later doses will be less effective than the first few doses.This is an example of

Accepted Answer

A)  drug disposition tolerance.
B)  behavioral tolerance.
C)  an active metabolite.
D)  a prodrug.E) A) and B)
F) None of the above A

Question 7

The text uses an example of overlapping dose-response curves for slowed reaction time,ataxia (staggering) ,and coma to illustrate

Accepted Answer

A)  how different drugs have different effects.
B)  that different drug-related effects can have different thresholds.
C)  the placebo effect.
D)  the grapefruit-juice effect.E) A) and B)
F) C) and D)

Question 8

What is the placebo effect? Describe some research techniques that have been developed to separate specific drug effects from placebo effects.

Accepted Answer

The placebo effect is an effect that doe...

Question 9

Which of the following would be a reason for a drug company NOT to pursue expensive clinical trails with a new drug?

Accepted Answer

A)  The drug produces no side effects.
B)  The drug produces side effects.
C)  The therapeutic index is greater than 1.
D)  The therapeutic index less than 1.E) All of the above
F) B) and C)

Question 10

The blood-brain barrier

Accepted Answer

A)  is fully developed in humans when they are born.
B)  is designed to allow all drug compounds into the brain.
C)  cannot be penetrated,even with trauma to the brain.
D)  prevents many drugs from entering the brain.E) None of the above
F) B) and C)

Question 11

For most therapeutic effects,there is a maximum effect,and increasing the dose more just increases the number and type of side effects.

Accepted Answer

A) True 
 B)False

Question 12

Most psychoactive drugs taken orally go directly from the stomach to the brain.

Accepted Answer

A) True 
 B)False  False

Question 13

The safety margin for a particular drug is based on the idea that

Accepted Answer

A)  toxic doses will typically be larger than therapeutic doses.
B)  most drugs cause toxicity problems only when combined with other drugs.
C)  we need to determine an LD50 using human volunteers.
D)  we should only prescribe drugs that are not toxic even at high doses.E) A) and B)
F) A) and D)

Question 14

When neither the person taking the drug nor the person evaluating the effects of the drug knows which people are getting the experimental drug and which people are getting the placebo,this procedure is referred to as a(n)

Accepted Answer

A)  design flaw.
B)  effect size.
C)  preclinical study.
D)  double-blind procedure.E) None of the above
F) A) and D)

Question 15

Concussions and cerebral infections can decrease the effectiveness of

Accepted Answer

A)  drug metabolism.
B)  the blood-brain barrier.
C)  protein binding.
D)  multiple drug doses.E) A) and B)
F) None of the above

Question 16

What kind of name is Provigil (an alerting drug) ?

Accepted Answer

A)  chemical name
B)  generic name
C)  brand name
D)  none of the aboveE) A) and D)
F) All of the above

Question 17

The story of the Michigan police officer who ate marijuana-laced brownies and then called 911,is a good illustration of which basic psychopharmacology fact?

Accepted Answer

A)  Drug laws only apply to those outside of law enforcement.
B)  Marijuana produces paranoia in the majority of users.
C)  The oral route of administration produces the fastest onset of effects.
D)  Different routes of administration can producing markedly different drug effects.E) A) and B)
F) None of the above

Question 18

If you want to get very high concentrations of cocaine to the brain very rapidly,which route of administration would you probably use?

Accepted Answer

A)  oral
B)  subcutaneous
C)  topical
D)  intravenousE) A) and C)
F) None of the above

Question 19

Of the following routes of administration,which will produce fastest onset of effects?

Accepted Answer

A)  inhalation.
B)  intramuscular injection.
C)  using a rectal suppository.
D)  rubbing it on the head.E) None of the above
F) A) and D)

Question 20

The most common way for drug molecules to be deactivated is by

Accepted Answer

A)  CYP450 enzymes in the liver.
B)  protein binding.
C)  elimination through the bowel.
D)  reuptake.E) A) and B)
F) None of the above

Exam 5: The Actions of Drugs

When use of a drug interferes with normal behavior,experienced users may learn to compensate and show less impairment than new users.This is an example of

Correct AnswerverifiedShow Answer

Caffeine and cocaine are both considered to be stimulant drugs.

Correct AnswerverifiedShow Answer

According to the text,inexperienced drug users should avoid taking a drug via a route that increases the drug's potency.

Correct AnswerverifiedShow Answer

With increasing doses of any useful drug,there is usually an increase in the number and severity of

Correct AnswerverifiedA

Nonspecific effects of taking a drug are those that do not depend on its chemical activity.They are sometimes referred to as

Correct AnswerverifiedShow Answer

If repeated exposure to a drug increases the activity of the CYP450 enzyme that is responsible for metabolizing that drug,then later doses will be less effective than the first few doses.This is an example of

Correct AnswerverifiedA

The text uses an example of overlapping dose-response curves for slowed reaction time,ataxia (staggering) ,and coma to illustrate

Correct AnswerverifiedShow Answer

What is the placebo effect? Describe some research techniques that have been developed to separate specific drug effects from placebo effects.

Correct AnswerverifiedThe placebo effect is an effect that doe...View AnswerShow Answer

Which of the following would be a reason for a drug company NOT to pursue expensive clinical trails with a new drug?

Correct AnswerverifiedShow Answer

The blood-brain barrier

Correct AnswerverifiedShow Answer

For most therapeutic effects,there is a maximum effect,and increasing the dose more just increases the number and type of side effects.

Correct AnswerverifiedShow Answer

Most psychoactive drugs taken orally go directly from the stomach to the brain.

Correct AnswerverifiedFalse

The safety margin for a particular drug is based on the idea that

Correct AnswerverifiedShow Answer

When neither the person taking the drug nor the person evaluating the effects of the drug knows which people are getting the experimental drug and which people are getting the placebo,this procedure is referred to as a(n)

Correct AnswerverifiedShow Answer

Concussions and cerebral infections can decrease the effectiveness of

Correct AnswerverifiedShow Answer

What kind of name is Provigil (an alerting drug) ?

Correct AnswerverifiedShow Answer

The story of the Michigan police officer who ate marijuana-laced brownies and then called 911,is a good illustration of which basic psychopharmacology fact?

Correct AnswerverifiedShow Answer

If you want to get very high concentrations of cocaine to the brain very rapidly,which route of administration would you probably use?

Correct AnswerverifiedShow Answer

Of the following routes of administration,which will produce fastest onset of effects?

Correct AnswerverifiedShow Answer

The most common way for drug molecules to be deactivated is by

Correct AnswerverifiedShow Answer

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A

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A

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The placebo effect is an effect that doe...
View Answer

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False

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