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Describe the sequence of events that occurs in synaptic transmission.

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Synthesis, storage, ...

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Which effect is consistently associated with a "second messenger"?


A) ionotropic
B) metabotropic
C) inhibitory
D) excitatory

E) B) and C)
F) A) and D)

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A drug that relaxes a person and makes them less sensitive to pain is most likely a(n) :


A) opiate.
B) hallucinogen.
C) stimulant.
D) cannabinoid.

E) A) and B)
F) All of the above

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Dopamine and norepinephrine are classified as:


A) second messengers.
B) purines.
C) proteins.
D) catecholamines.

E) All of the above
F) A) and B)

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Which of the following is NOT a factor in determining whether or not two EPSPs combine to reach threshold?


A) size of the EPSPs
B) timing between them
C) threshold of the postsynaptic cell
D) threshold of the presynaptic cell

E) A) and B)
F) None of the above

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Gases can be used as neurotransmitters.

A) True
B) False

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Depolarization is to ____ as hyperpolarization is to ____.


A) excitation; inhibition
B) inhibition; excitation
C) increasing the threshold; decreasing the threshold
D) decreasing the threshold; increasing the threshold

E) None of the above
F) All of the above

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Even at rest, most neurons have periodic production of action potentials, known as the:


A) spontaneous firing rate.
B) excitatory firing rate.
C) all-or-none law.
D) Dale's principle.

E) B) and C)
F) A) and B)

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The proper order of a reflex arc is:


A) motor neuron, sensory neuron, interneuron.
B) sensory neuron, motor neuron, interneuron.
C) motor neuron, interneuron, sensory neuron.
D) sensory neuron, interneuron, motor neuron.

E) B) and C)
F) A) and D)

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Briefly describe spatial summation.

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Our brains respond to plant chemicals because:


A) plants use chemicals similar to neurotransmitters.
B) animals evolved from plants.
C) plants have evolved neuron-like cells.
D) those are the only chemicals that are stable at common environmental temperatures.

E) A) and B)
F) All of the above

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Which of the following is NOT a likely effect of using marijuana?


A) memory loss
B) decreased nausea
C) reduced risk of Parkinson's disease
D) suppressed appetite

E) A) and C)
F) None of the above

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A drug that blocks the effects of a neurotransmitter is an agonist.

A) True
B) False

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To measure temporal summation in single cells, researchers:


A) attach electrodes to the scalp.
B) insert an microelectrode into the scalp.
C) collect sodium and potassium ions from nearby glial cells.
D) record depolarizations of the postsynaptic neuron.

E) A) and B)
F) A) and C)

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If a drug has high affinity and high efficacy, what effect does it have on the postsynaptic neuron?


A) antagonistic
B) agonistic
C) proactive
D) destructive

E) C) and D)
F) A) and B)

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Which of the following is TRUE about the spontaneous firing rates of neurons?


A) EPSPs increase the frequency.
B) EPSPs decrease the frequency.
C) IPSPs increase the frequency.
D) One EPSP equals the effect of two IPSPs.

E) A) and B)
F) C) and D)

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Neurotransmitter is to ____ as cyclic AMP is to ____.


A) first messenger, second messenger
B) second messenger, first messenger
C) metabotropic, ionotropic
D) receptor, neuromodulator

E) None of the above
F) All of the above

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In addition to influencing other neurons, ____ dilates the nearby blood vessels, thereby increasing blood flow to that area of the brain.


A) endorphins
B) glycine
C) nitric oxide
D) acetylcholine

E) All of the above
F) B) and C)

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Describe the main properties of neuropeptides (neuromodulators).

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What is the synaptic cleft?


A) the gap between the presynaptic neuron and the postsynaptic neuron
B) a packet that stores neurotransmitter molecules
C) a subthreshold depolarization
D) the storage location for calcium ions

E) All of the above
F) A) and B)

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