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Which process is responsible for the release of neurotransmitters from the presynaptic neuron into the synapse?


A) diffusion
B) endocytosis
C) exocytosis
D) fusion
E) synaptic release

F) B) and E)
G) None of the above

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Explain how the resting membrane potential and resting ion distributions are established in a neuron.

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A resting membrane potential of -70 mV i...

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The additive effect of one neuron sending many EPSPs to another neuron over a brief period of time is called spatial summation .

A) True
B) False

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An action potential is propagated down an unmyelinated neuronal plasma membrane because it stimulates voltage-gated ____ channels adjacent to it. (Choose the most accurate answer.)


A) Na+
B) Ca2+
C) K+
D) Na+and Ca2+
E) K+and Ca2+

F) A) and D)
G) B) and D)

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The intensity of an electrical impulse is reflected in the ____ of action potentials.


A) frequency
B) magnitude
C) duration
D) intensity
E) the frequency and duration

F) C) and D)
G) A) and D)

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  Figure 39.1 -Answer the question using the accompanying figure. At which point in this action potential diagram does the onset of Na<sup>+</sup>channel inactivation stop the inward flow of Na<sup>+</sup>? A)  A B)  B C)  C D)  D E)  E Figure 39.1 -Answer the question using the accompanying figure. At which point in this action potential diagram does the onset of Na+channel inactivation stop the inward flow of Na+?


A) A
B) B
C) C
D) D
E) E

F) A) and B)
G) A) and D)

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As the action potential peaks, ____.


A) the activation gates of Na+channels close
B) the inactivation gates of Na+channels close
C) the activation gates of K+channels close
D) Na+/K+active transport pumps are activated

E) B) and C)
F) A) and D)

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If the equilibrium potential is close to the resting membrane potential, the net ionic movement across the membrane will be very small.

A) True
B) False

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Explain how neuron action potential propagation rate can be increased.

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Neuron action potential propagation can be increased in two ways: (1) by increasing axonal diameter, and (2) myelinating the axon. Increased axonal diameter reduces electrical resistance to current flow. Myelination causes an electrical current to "jump" from one node of Ranvier to the next by saltatory conduction, which is more rapid than conduction in an unmyelinated neuron.

In an effort to determine the mechanism of neuronal signaling, Otto Loewi isolated ____.


A) frog hearts
B) frog brains
C) rat hearts
D) rat brains
E) rat vagus nerve

F) A) and D)
G) D) and E)

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Which neuronal structure has the greatest density of voltage-gated Na+channels, resulting in the lowest threshold potential along a neuron?


A) dendrites
B) cell body
C) axon hillock
D) axon
E) axon terminals

F) A) and B)
G) A) and E)

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Most neurons that release GABA and glycine are ____.


A) astrocytes
B) projection neurons
C) interneurons
D) oligodendrocytes
E) Schwann cells

F) D) and E)
G) A) and B)

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What is the typical resting potential of an isolated neuron?


A) -60 mV
B) -70 mV
C) -80 mV
D) -90 mV
E) 100 mV

F) A) and B)
G) None of the above

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B

A graded, subthreshold change in the postsynaptic membrane potential that moves it toward threshold is called a(n) ____.


A) IPSP
B) hyperpolarization
C) EPSP
D) depolarization
E) repolarization

F) All of the above
G) A) and C)

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Which neurotransmitter is most likely to be inhibitory?


A) glutamate
B) dopamine
C) Substance P
D) GABA
E) acetylcholine

F) C) and D)
G) A) and B)

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Where are most synapses formed?


A) on the dendrites of postsynaptic neurons
B) on cell bodies
C) on axon terminals
D) on oligodendrocytes
E) on Schwann cells

F) D) and E)
G) None of the above

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Place the events in chemical synapse transmission in the correct order. (1)   Ca2+enters axon terminal. (2)   Ligand-gated ion channels open in postsynaptic membrane. (3)   Neurotransmitter binds to postsynaptic receptor. (4)   Action potential reaches axon terminal of presynaptic neuron. (5)   Neurotransmitter released by exocytosis.


A) 4, 1, 5, 3, 2
B) 4, 3, 1, 5, 2
C) 4, 5, 1, 3, 2
D) 4, 1, 3, 5, 2
E) 4, 5, 2, 3, 1

F) A) and E)
G) D) and E)

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Oligodendrocytes are responsible for myelinating central nervous system axons.

A) True
B) False

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True

Which cells assist and nourish neurons that transmit electrical signals?


A) receptor cells
B) neurons
C) effector cells
D) glial cells
E) signal cells

F) C) and D)
G) B) and C)

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  Figure 39.1 -Answer the question using the accompanying figure. At which point in this action potential diagram does the K<sup>+</sup>channel close to stabilize the membrane potential? A)  A B)  B C)  C D)  D E)  E Figure 39.1 -Answer the question using the accompanying figure. At which point in this action potential diagram does the K+channel close to stabilize the membrane potential?


A) A
B) B
C) C
D) D
E) E

F) A) and C)
G) A) and E)

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