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Which of the following is a goal of the Human Genome Project?


A) To develop technological advances in molecular genetics
B) To analyze the genomes of model organisms
C) To obtain a physical map of the human genome
D) To obtain the DNA sequence of the human genome
E) All of the answers are correct

F) B) and E)
G) B) and C)

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The likelihood of linkage between two genes is determined using a analysis.


A) chi-square
B) linkage
C) shotgun
D) binomial expansion
E) lod score method

F) B) and D)
G) A) and D)

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A series of clones that contain overlapping pieces of a chromosome are called a .


A) contig
B) artificial chromosome
C) cosmid
D) positional clone
E) transposable element

F) A) and B)
G) A) and C)

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If all members of a population have the identical DNA segment, it is said to be .


A) Monomorphic
B) Polymorphic
C) Trimorphic
D) None of the answers are correct

E) B) and D)
F) A) and D)

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uses the unique banding patterns of a chromosome to determine the general location of a gene.


A) Physical mapping
B) Cytogenetic mapping
C) Linkage mapping
D) All of the answers are correct

E) A) and B)
F) A) and C)

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Which of the following would generally not be used as a marker in a linkage mapping experiment?


A) RFLPs
B) VNTRs
C) STRs
D) FISH
E) STS

F) A) and B)
G) A) and C)

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Bioinformatics refers to the molecular analysis of the entire genome of a species.

A) True
B) False

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Which of the following terms best describes how the components of a genome interact to produce an organism's traits?


A) Proteomics
B) Functional genomics
C) Structural genomics
D) Genomics

E) None of the above
F) A) and B)

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The human genome project's first draft took approximately years.


A) 5
B) 13
C) 20
D) 50
E) 2

F) C) and D)
G) B) and D)

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The most common micro satellite in humans is .


A) (AT) 100
B) (CA) n
C) (TG) n
D) (CAT) n
E) None of the answers are correct

F) B) and C)
G) C) and E)

Correct Answer

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If a lod score method indicates that two genes are linked the nucleotide distance between the genes can be determined by determining the frequency of recombination between the genes.

A) True
B) False

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