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A homozygous tomato plant with red fruit and yellow flowers was crossed with a homozygous tomato plant with golden fruit and white flowers. The F₁ all had red fruit and yellow flowers. The F₁ were testcrossed by crossing them to homozygous recessive individuals, and the following offspring were obtained: Red fruit and yellow flowers-41 Red fruit and white flowers-7 Golden fruit and yellow flowers-8 Golden fruit and white flowers-44 How many map units separate these genes?


A) 17.6
B) 15
C) 17.1
D) 18.1

E) B) and D)
F) A) and D)

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Inheritance patterns cannot always be explained by Mendel's models of inheritance. If a pair of homologous chromosomes fails to separate during meiosis I, select the choice that shows the chromosome number of the four resulting gametes with respect to the normal haploid number (n) ?


A) n + 1; n + 1; n - 1; n - 1
B) n + 1; n - 1; n; n
C) n + 1; n - 1; n - 1; n - 1
D) n + 1; n + 1; n; n

E) C) and D)
F) B) and C)

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German scientist Carl Correns found that the inheritance of variegated color on the leaves of certain plants was determined only by the maternal parent. What phenomenon explains this pattern of inheritance?


A) ribosome structure
B) inheritance of plastid genes
C) genomic imprinting
D) sex linkage

E) C) and D)
F) B) and D)

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All female mammals have one active X chromosome per cell instead of two. What causes this to happen?


A) activation of the XIST gene on the X chromosome that will become the Barr body
B) activation of the BARR gene on one X chromosome, which then becomes inactive
C) inactivation of the XIST gene on the X chromosome derived from the male parent
D) attachment of methyl (-CH₃) groups to the X chromosome that will remain active

E) A) and B)
F) A) and C)

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Generally, only female cats have the tortoiseshell phenotype for fur color. Which of the following statements explains this phenomenon?


A) A male inherits only one allele of the X-linked gene controlling hair color.
B) The Y chromosome has a gene blocking orange coloration.
C) Only males can have Barr bodies.
D) Multiple crossovers on the Y chromosome prevent orange pigment production.

E) A) and B)
F) A) and C)

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Which of the following statements regarding gene linkage is correct?


A) The closer two genes are on a chromosome, the lower the probability that a crossover will occur between them.
B) The observed frequency of recombination of two genes that are far apart from each other has a maximum value of 100%.
C) All of the traits that Mendel studied-seed color, pod shape, flower color, and others-are due to genes linked on the same chromosome.
D) Linked genes are found on different chromosomes.

E) B) and C)
F) A) and D)

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During meiosis, a defect occurs in a cell that results in the failure of spindle microtubules binding at the kinetochores. Which of the following statements describes the most likely result of such a defect?


A) New microtubules with more effective binding capabilities to kinetochores will be synthesized to compensate for the defect.
B) Excessive cell divisions will occur resulting in cancerous tumors and an increase in the chromosome numbers known as polyploidy.
C) The defect will be bypassed in order to ensure normal chromosome distribution in the new cells.
D) The resulting cells will not receive the correct number of chromosomes in the gametes, a condition known as aneuploidy.

E) C) and D)
F) B) and C)

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Use the following information to answer the question. A plantlike organism on the planet Pandora can have three recessive genetic traits: bluish leaves, due to an allele (a) of gene A; a feathered stem, due to an allele (b) of gene B; and hollow roots due to an allele (c) of gene C. The three genes are linked and recombine. A geneticist performed a testcross with an organism that had been found to be heterozygous for the three recessive traits, and she was able to identify progeny of the following phenotypic distribution (+ = wild type) : Use the following information to answer the question. A plantlike organism on the planet Pandora can have three recessive genetic traits: bluish leaves, due to an allele (a)  of gene A; a feathered stem, due to an allele (b)  of gene B; and hollow roots due to an allele (c)  of gene C. The three genes are linked and recombine. A geneticist performed a testcross with an organism that had been found to be heterozygous for the three recessive traits, and she was able to identify progeny of the following phenotypic distribution (+ = wild type) :   Which of the following are the phenotypes of the parents in this cross? A)  2 and 5 B)  1 and 6 C)  4 and 8 D)  3 and 7 Which of the following are the phenotypes of the parents in this cross?


A) 2 and 5
B) 1 and 6
C) 4 and 8
D) 3 and 7

E) A) and B)
F) None of the above

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In Drosophila melanogaster, vestigial wings are determined by a recessive allele of a gene that is linked to a gene with a recessive allele that determines black body color. T. H. Morgan crossed black-bodied, normal-winged females and gray-bodied, vestigial-winged males. The F₁ were all gray bodied, normal winged. The F₁ females were crossed to homozygous recessive males to produce testcross progeny. Morgan calculated the map distance to be 17 map units. Which of the following information is correct about the testcross progeny?


A) black-bodied, normal-winged flies = 17% of the total
B) black-bodied, normal-winged flies plus gray-bodied, vestigial-winged flies = 17% of the total
C) gray-bodied, normal-winged flies plus black-bodied, vestigial-winged flies = 17% of the total
D) black-bodied, vestigial-winged flies = 17% of the total

E) A) and B)
F) A) and C)

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Which of the following statements correctly describes what happens to a chromosome after a nonreciprocal translocation occurs?


A) A deletion of part of the chromosome occurs.
B) A duplication of part of the chromosome occurs.
C) Nondisjunction of pairs of homologous occurs.
D) A chromosome transfers a fragment but receives none in return.

E) C) and D)
F) B) and C)

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Use the following information to answer the question. A plantlike organism on the planet Pandora can have three recessive genetic traits: bluish leaves, due to an allele (a) of gene A; a feathered stem, due to an allele (b) of gene B; and hollow roots due to an allele (c) of gene C. The three genes are linked and recombine. A geneticist performed a testcross with an organism that had been found to be heterozygous for the three recessive traits, and she was able to identify progeny of the following phenotypic distribution (+ = wild type) : Use the following information to answer the question. A plantlike organism on the planet Pandora can have three recessive genetic traits: bluish leaves, due to an allele (a)  of gene A; a feathered stem, due to an allele (b)  of gene B; and hollow roots due to an allele (c)  of gene C. The three genes are linked and recombine. A geneticist performed a testcross with an organism that had been found to be heterozygous for the three recessive traits, and she was able to identify progeny of the following phenotypic distribution (+ = wild type) :   If recombination frequency is equal to distance in map units, what is the approximate distance between genes A and B? A)  3 map units B)  6 map units C)  15 map units D)  30 map units If recombination frequency is equal to distance in map units, what is the approximate distance between genes A and B?


A) 3 map units
B) 6 map units
C) 15 map units
D) 30 map units

E) A) and B)
F) B) and D)

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One possible result of chromosomal breakage is for a fragment to join a nonhomologous chromosome. What is this type of chromosomal alteration called?


A) deletion
B) inversion
C) translocation
D) duplication

E) B) and D)
F) B) and C)

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In birds, sex is determined by a ZW chromosome scheme. Males are ZZ and females are ZW. A recessive lethal allele that causes death of the embryo is sometimes present on the Z chromosome in pigeons. What would be the sex ratio in the offspring of a cross between a male that is heterozygous for the lethal allele and a normal female?


A) 2:1 male to female
B) 1:2 male to female
C) 1:1 male to female
D) 3:1 male to female

E) A) and B)
F) A) and C)

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A certain kind of snail can have a right-handed direction of shell coiling (DD or Dd) or left-handed coiling (dd) . However, if direction of coiling is due to a protein deposited by the mother in the egg cytoplasm, then a Dd egg-producing snail and a dd sperm-producing snail will have offspring of which genotype(s) and phenotype(s) ?


A) 1/2 Dd:1/2 dd; all right-coiling
B) all Dd; all right-coiling
C) 1/2 Dd: 1/2 dd; half right-coiling and half left-coiling
D) all Dd; half right-coiling and half left-coiling

E) C) and D)
F) B) and D)

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Glucose-6-phosphate dehydrogenase deficiency (G6PD) is inherited as an X-linked recessive allele in humans. A woman whose father suffered from G6PD marries a normal man. What proportion of their sons is expected to be G6PD?


A) 100%
B) 1/4
C) 1/2
D) zero

E) None of the above
F) A) and B)

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Of the following human aneuploidies, which is the one that generally has the most severe impact on the health of the individual?


A) 47, trisomy 21
B) 47, XXY
C) 47, XXX
D) 45, X

E) A) and D)
F) All of the above

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Use the following information to answer the question. Use the following information to answer the question.   In a series of mapping experiments, the recombination frequencies for four different linked genes of Drosophila were determined as shown in the figure. Based on this information, what is the order of these genes on a chromosome map? A)  rb-cn-vg-b B)  cn-rb-b-vg C)  b-rb-cn-vg D)  vg-cn-b-rb In a series of mapping experiments, the recombination frequencies for four different linked genes of Drosophila were determined as shown in the figure. Based on this information, what is the order of these genes on a chromosome map?


A) rb-cn-vg-b
B) cn-rb-b-vg
C) b-rb-cn-vg
D) vg-cn-b-rb

E) B) and C)
F) All of the above

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In cats, black fur color is determined by an X-linked allele; the other allele at this locus determines orange color. The heterozygote is tortoiseshell. What kinds of offspring would you expect from the cross of a black female and an orange male?


A) tortoiseshell females; tortoiseshell males
B) black females; orange males
C) tortoiseshell females; black males
D) orange females; black males

E) B) and D)
F) All of the above

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